Project: MAGIC

The Meta-Analyses of Glucose and Insulin-related traits Consortium was formed to identify the genetic determinants of quantitative glycemic traits in non-diabetic individuals. It has discovered multiple loci influencing fasting and dynamic masures of glycemia, insulin secretion and insulin action, as described in the publications section. In doing so, it has provided a rich dataset in which to examine the physiological impact of T2D-associated variants, or variants associated with other phenotypes.

Genetic Discovery